Curcumin is derived from the herb known as Curcuma longa or turmeric. This rhizomatous herbaceous plant is part of the ginger family and is indigenous to southeast India. More specifically Curcumin is an active ingredient of the Curcuma longa plant’s root. Curcumin, the active ingredient of turmeric, has long been used in Asian medicine as a remedy to a variety of aliments.
As of the summer of 2014 according to www.clinicaltrials.gov there were 33 active clinical trials (16 in the United States) using Curcumin as an intervention drug in a wide variety of diseases.
Curcumin has been widely used for many years as a nutritional supplement due to its many health benefits. As early as the seventh century reports were found of curcumin’s use in Asian and Indian medicine.
However, in recent years numerous scientific studies have produced credible data suggesting that when Curcumin is administered in its natural state the supplement’s bioavailability is less than optimal. Studies over the past three decades credited curcumin with poor absorption and high metabolism rates severely decreasing its effects within the body. These studies found that natural curcumin is easily broken down by enzymes within the human intestine, liver, and tissues converting the molecule into inactive metabolites that are quickly eliminated from the body. Therefore, those wishing to amass the maximum beneficial effects from curcumin would have to consume the supplement in large quantities on a daily bases.
Liposomal curcumin can solve these bioavalibility dilemma. By incorporating curcumin, a fat-soluble molecule, into the lipid bilayer of the liposome, the supplement is able to increase the circulation and subsequently the absorption rate of the liposome’s active ingredient, curcumin. Encapsula NanoSciences also takes the formulation one step further by incorporating both piperine and quercetin. Piperine, black pepper, and quercetin (plant extract), are the key components that inhibit the enzymes that make curcumin inactive. Furthermore CurcusomeTMcontains phosphatidylcholine which is a natural chemical found throughout the human body. Phosphatidylcholine is used to create acetylcholine, an important chemical in the brain. CurcusomeTM not only increases the solubility and bioavailability of all three molecules but also delivers all three molecules to the gastrointestinal tract where they are absorbed and utilized to their full extent.
Academic studies have suggested that the mucoadhesive formulation of the curcumin liposomes will stay in the intestine longer than free curcumin and therefore more curcumin is absorbed by the body.
In addition, the liposomal formulation can allow for more active curcumin to be delivered in one dose. Commercially available dried turmeric roots only contain between 3-5% curcumin. Encapsula NanoSciences, on the other hand, is able to use a purified curcmin turmeric extract that is 95% pure. This enables the consumer to receive a higher dose of curcumin while actually taking less. With Encapsula’s ingenious, powder release caps consumers can drink one bottle of water of CurcusomeTM and receive greater benefits than taking multiple capsules a day of similar supplemental products.
For over 1000 years curcumin has been used in medicinal practices. As of the summer of 2014 according to www.clinicaltrials.gov there were 33 active clinical trials (16 in the United States) using Curcumin as an intervention drug in a wide variety of diseases. Research done with laboratory animals has shown that curcumin can help lower “bad” cholesterol, act as an anti-inflammatory agent, reduce symptoms of arthritis and help with ulcerative colitis. Initial animal studies showed that the administration of curcumin helped to block the plaques and proteins in the brain that are involved in the onset of Alzheimer’s disease. In addition laboratory studies over the years have proven that curcumin effects several molecular pathways involved in the development and spread of cancer. In these studies the use of curcumin has been shown to reduce the growth rate of cancer cells and even diminish tumor size in some animals. The tumor sites studied include the mouth, intestines, skin, breast, esophagus, and stomach. These results are very encouraging, however further studies in humans are needed. Currently human clinical trials studying the effects of curcumin for the prevention and treatment of several diseases are in the early stages.
Curcumin Health Benefits Quick List:
– Anti-Inflammatory Response.*
– Powerful Antioxidant.*
– Supports Brain Function.*
– Promotes Heart Health.*
– Maintains Liver Health.*
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