Resveratrol is an phytoalexin compound that is commonly found in nature specifically in peanuts and a large variety of fruits such as blueberries and cranberries. Resveratrol can also be extracted from the dried root of Japanese and Chinese knotweed plants from the Polygonum cuspidatum family. The most well known and commercialized source of resveratrol is extracted from the skin of red grapes and is the key beneficial component in red wine.
For centuries grapes and grape juice have been touted by herbalist and medical professionals as beneficial in maintaining a healthy lifestyle. Japanese and Chinese traditional medicine has used resveratrol extracts to treat an assortment of ailments for over 1,500 years.
Even so it was not really until the early nineties that today’s scientist started to study and understand the mechanisms by which resveratrol works in earnest. This was due in large part to the phenomena that became known as the “French paradox”. Studies showed that most of the population of France was less susceptible to heart disease than in other parts of the world. This was intriguing as a large population of France on a regular basis eats a high fat diet; a diet that is normally connected with heart disease. After studies were completed the apparent cardioprotection was attributed to the regular consumption of Resveratrol through moderate doses of red wine.
Different red wines contain varying amounts of resveratrol depending upon the type of grapes used in the fermentation process. It has been reported that the range of resveratrol is between 0.43 and 12.59 milligrams per liter. White wine due to the fact that the process is shorter only has between 0.05 and 1.8 milligrams per liter. Needless to say you would have to intake a lot of wine to achieve the dosage needed to receive health benefits.
Current studies suggest that the average daily intake of humans of resveratrol ranges anywhere from 40mg of resveratrol a day to 500mg; even at the low end a person would need to consume a little over 3 liters of red wine a day. The benefit of ResverasomeTM is that it is made from a purified extract and is delivered in a liposomal form so that it is able to be fully absorbed and dispersed inside the human body.
Another issue with other resveratrol products is the poor bioavailability of the molecule. Resveratrol is known to be both quickly broken down inside the human body, making it inactive, and also to be poorly absorbed. This means that even when you are taking large doses of resveratrol very little health benefits are seen because your body is unable to absorb the molecule. ResverasomeTM fixes these issues by supplying the molecule in a liposomal form. The liposome acts as a casing around the molecule protecting it from degrading enzymes in the human gut. In addition ResverasomeTM contains piperine, quercetin, 90% wine polyphenol, and phosphatidylcholine. Piperine, black pepper, and quercetin a plant extract, are the key components that inhibit the enzymes in the gut that can make resveratrol inactive. Furthermore ResverasomeTM contains phosphatidylcholine which is a natural chemical found throughout the human body. Phosphatidylcholine is used to create acetylcholine, an important chemical in the brain. ResverasomeTM not only increases the solubility and bioavailability of all four molecules but also delivers all of them to the gastrointestinal tract where they are absorbed and utilized to their full extent.
As of the summer of 2014 according to www.clinicaltrials.gov there were 30 active clinical trials (26 in North America and Europe) using Resveratrol as an intervention drug in a wide variety of diseases. Resveratrol is a strong antioxidant. Scientists believe this is because the molecule promotes an increase in the body’s nitric oxide synthesis. Nitric oxide is one of the bodies most powerful, naturally occurring, antioxidants.
Resveratrol has also been shown to improve and promote good heart health within the laboratory. In rats given resveratrol scientist noted improved postischemic ventricular function, reduced cardiomyocyte cell death, and reduced myocardial infarction. Furthermore studies have shown that obese rats given resveratrol showed less obesity related cardiac injury than did their counterparts who did not receive resveratrol. This is a promising result as heart health is a major concern in diabetics and obese individuals.
Several promising animal studies showed that doses of resveratrol could possess neuroprotective properties; this would be important for individuals with Huntington’s disease , Alzheimer’s disease and Parkinson’s disease.
There were also several encouraging studies that claimed that resveratrol could aid in the longevity of life. Scientist saw an increased lifespan in various animal species given resveratrol. Some of the species include Drosophila, C. elgans as well as Northobranchius (small short-lived fish) and mice. So how does resveratrol accomplish this; scientist believe that the molecule activates the Sirtuins (SIRT) genes that are known to promote longevity assurances. Several age related diseases have been studies such as type 2 diabetes, neurodegeneration, inflammation, and cardiovascular disease, all with positive results.
When given in high doses resveratrol has been shown to have anticancer effects in various cancer cell lines. Resveratrol has been shown to support the inhibition of cancer cell initiation, proliferation and aid in slowing cancer progression. Various cell lines have been studied both in vitro and in vivo, among them are cancer cells related to colorectal cancer, prostate cancer, neuroblastoma, multiple myeloma, breast cancer (both estrogen negative and positive) and T-cell acute lymphoblastic leukemia.
Resveratrol Health Benefits Quick List :
-High potency free radical*
-Proven to trigger SIRT1 (a serum that blocks diseases by speeding up the cell’s energy production centers known as mitrochondria) longevity gene*
-Supports healthy aging*
-Promotes heart health*
-Helps maintain the structural integrity of capillaries and connective tissue*
-Helps maintain optimum cholesterol levels*
Copyright by Encapsula NanoSciences 2014
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